Leukemia Treatment Cost-Effectiveness Model

Enter baseline values below for age at diagnosis, cost of hydroxyurea ($), cost of interferon including administration ($), the annual discount rate (0–1), and the utility of Interferon treatment (0–1).

Also, enter high and low values for the utility of Interferon treatment, in order to define a range for sensitivity analysis on this variable.

Costs Cost of Hydroxyurea (dollars per month) (50–300)   Cost of Interferon and Administration (dollars per month) (500–2500) ? Utilities Interferon (flu-like symptoms) (0–1)   Other Parameters Annual Discount Rate (0–0.2)   1-Way Sensitivity Analysis Age at Diagnosis (in years) (10–90)   low high

(NOTE: For the purposes of this demonstration, the Markov process terminates after 100 cycles/months. A full analysis would run from 5 to 10 times longer, in order to model an entire "life cycle." The full Markov process would tend to decrease the Interferon treatment option's marginal cost-effectiveness ratio.)